Alright, it doesn’t look so simple from the above image, but on 25 January, Tottori University announced that researchers have found a method to successfully transform a cancerous tumor into non-threatening tissue. Although the research that went into it is incredibly complicated, the result is a single molecule that may be able to universally reverse cancerous cells in a relatively brief amount of time.
The announcement doesn’t hold back its enthusiasm either,
proclaiming that from this discovery “the dream of the eradication of cancer is
at hand.”
■ RNA
The bulk of this research centers on RNA. There are
different types of RNA, such as messenger RNA molecules which work to send
information from an organism’s DNA to the ribosomes which begin to create
proteins for specialized cell production.
Also in the mix are microRNA molecules. The smaller strands
connect with messenger RNA and can inhibit the production of proteins. This
helps to regulate the growth of cells in our body. However, microRNA when
working in a different way can also interfere with a cell’s natural destruction
potentially leading to cancerous tumors.
The exact way this happens is very complex and the challenge
for cancer researchers is finding which type(s) of microRNA triggers or impedes
the development of cancers.
■ microRNA-520d
The work done at Tottori University focused on Human
microRNA-520d (miR-520d) about which not a whole lot is known. Still, they
suspected that it held the power to control whether cells were cancerous or
not.
In various mice experiments, it was found that miR-520d
indeed transformed their cancer cells in either regular tissue cells or benign
tumors completely. Not only that; for undifferentiated liver cancer the
transformation only took 12 hours. More complex cancers were said to take up to
a month to be converted into non-cancerous matter.
▼ Chart showing results of miR-520d versus a mock
injection, 520d led to a combination of non-cancerous cells whereas the mock
substance resulted in 100 percent cancer development
Experiments were also carried out on pancreatic cancer
cells, brain tumors, and malignant melanoma cells. All of which were easily
eliminated. The team feels confident that by the correct introduction of
miR-520d all cancers can be reversed. They also feel the simplicity of such a
treatment would alleviate the mental anguish of possible relapses that cancer
survivors must live with.
■ Reaction
Netizens were full of emotions at this announcement calling
it “historical” and “an amazing feat of medical technology.” Others remained
skeptical saying: “I’ll wait until the announcement of a it actually being
used.” And of course it wouldn’t be the internet without some smartass comments
such as: “Oh no, more elderly people!” and, “I hope this doesn’t raise my age
of retirement.”
It’s still early days, but if these results can occur in
humans without any serious negative effects, miR-520d could be a remarkable
game-changer for the world.
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